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4), hydrodynamic diameter (Fig

The column was eluted for 023 minutes with a linear gradient from 10% to 32% B

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demonstrated the efficacy of andrographolide, a diterpene lactone, in protecting the blood-brain barrier by inhibiting the CypA-NF-B-MMP-9 pathway, highlighting its dual anti-inflammatory and neuroprotective effects (Zhou X et al., 2024)